FridAI – Agents talking to Agents – Business Brain 799

In this episode of Business Brain, we look at a future where most internet traffic is agents talking to agents, and what that means for you. When your customer’s AI agent hits a roadblock trying to book or buy from you, it simply goes somewhere else. Dave shares how he had Claude build an MCP connector for his company’s backend in about 30 minutes while he sat through a conference session. We break down why agents are becoming store-agnostic, why Amazon is resisting while Shopify and Salesforce are opening the doors, and why the time to make your business agent-ready is now.

Then we turn to the single move that could level up your entire AI world: a chief of staff agent. Shannon explains how his GrokBot chief of staff spins up specialized helpers like a DM manager and a YouTube desk, while Dave compares notes on building his own inside Claude. We also cover Project Mini-Me, an app that watches your screen and listens all day, with a clear-eyed warning about what you should block from it. Hand off the busywork, choose how you spend your time, and keep living that Charmed Life.

• 00:00:00 Business Brain – The Entrepreneurs’ Podcast #799 for Casual FridAI, October 23rd, 2026
  • October 23rd: National Slap Your Coworker Day
• 00:01:36 Agents talking to agents
  • Instinct
  • Muse
  • Grok Bot
  • Somos Salsa
  • Shopify is well-poised to let your agent buy (amazon is not)
• 00:11:41 SPONSOR: Perplexity Computer. Start your free trial of Perplexity Computer today at https://PPLX.ai/brain and experience the next phase of AI. #ad
• 00:13:07 SPONSOR: NordLayer AI Scout helps organizations understand, govern, and protect AI usage by making AI activity visible across the entire workforce – web and desktop. https://nordlayer.com/ai-scout/businessbrain
• 00:14:38 Build yourself a Chief-of-Staff agent
  • Start with your Chief of Staff first
• 00:18:52 Be very aware what you share with new ambient capture apps like minimi
  • Project minimi
• 00:21:53 Managing Your Chief-of-Staff
• 00:24:31 Business Brain 799 Outtro
  • This Episode’s Big Takeway: Prepare your business for agents…and get yourself a Chief-of-Staff agent
  • Check out Business Brain Blueprints
  • Tell Your Friends!
  • Business Blueprints
  • Review Business Brain
  • Subscribe to the show
  • [email protected]
  • Call/Text: (567) 274-6977
• X/Twitter: @ShannonJean & @DaveHamilton, & @BizBrainShow
• LinkedIn: Shannon Jean, Dave Hamilton, & Business Brain
• Facebook: Dave Hamilton, Shannon Jean, & Business Brain

Podcast: Play in new window | Download (Duration: 25:49 — 18.1MB) | Embed

Subscribe: Apple Podcasts | Spotify | Podcast Index | RSS | More